David J Handelsman Selected Research

Dihydrotestosterone (Androstanolone)

1/2022	Controlled dual release of dihydrotestosterone and flutamide from polycaprolactone electrospun scaffolds accelerate burn wound healing.
8/2020	Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice.
12/2018	Lower Circulating Androgens Are Associated with Overall Cancer Risk and Prostate Cancer Risk in Men Aged 25-84 Years from the Busselton Health Study.
1/2018	Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer Xenografts.
1/2018	Testosterone, frailty and physical function in older men.
1/2018	Androgen action augments ischemia-induced, bone marrow progenitor cell-mediated vasculogenesis.
1/2017	Higher Dihydrotestosterone Is Associated with the Incidence of Lung Cancer in Older Men.
10/2016	Neutral associations of testosterone, dihydrotestosterone and estradiol with fatal and non-fatal cardiovascular events, and mortality in men aged 17-97 years.
1/2016	Elevated expression of the Sertoli cell androgen receptor disrupts male fertility.
1/2015	Testosterone, dihydrotestosterone and estradiol are differentially associated with carotid intima-media thickness and the presence of carotid plaque in men with and without coronary artery disease.

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David J Handelsman Research Topics

Disease

22	Frailty 01/2022 - 11/2008
16	Prostatic Neoplasms (Prostate Cancer) 11/2022 - 01/2005
11	Obesity 01/2022 - 06/2007
10	Cardiovascular Diseases (Cardiovascular Disease) 02/2022 - 06/2003
9	Neoplasms (Cancer) 10/2022 - 09/2008
9	Hyperandrogenism 01/2022 - 05/2012
8	Myocardial Infarction 02/2022 - 01/2014
8	Body Weight (Weight, Body) 01/2022 - 09/2006
8	Cognitive Dysfunction 10/2018 - 07/2009
7	Hypogonadism (Hypergonadotropic Hypogonadism) 07/2021 - 08/2016
6	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2022 - 05/2016
6	Type 2 Diabetes Mellitus (MODY) 01/2021 - 09/2014
5	Dementia (Dementias) 10/2022 - 01/2012
5	Heart Failure 02/2022 - 01/2014
5	Sarcopenia 10/2021 - 07/2015
5	Insulin Resistance 01/2021 - 01/2003
5	Ischemia 01/2019 - 06/2003
5	Carcinogenesis 01/2019 - 06/2012
5	Atherosclerosis 01/2015 - 07/2002
4	Hypertrophy 01/2022 - 10/2009
4	Pain (Aches) 10/2021 - 03/2010
4	Overweight 01/2021 - 01/2019
4	Infertility (Sterility) 01/2021 - 09/2007
4	Schizophrenia (Dementia Praecox) 01/2021 - 08/2012
4	Breast Neoplasms (Breast Cancer) 09/2020 - 06/2003
4	Erectile Dysfunction 04/2017 - 05/2004
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2016 - 01/2003
4	Osteoporosis 01/2015 - 01/2008
3	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 06/2012
3	Ischemic Stroke 02/2022 - 01/2021
3	Burns 01/2022 - 08/2020
3	Hypertension (High Blood Pressure) 01/2022 - 02/2010
3	Inflammation (Inflammations) 01/2022 - 07/2002
3	Virilism (Virilization) 12/2021 - 01/2002
3	Chronic Pain 10/2021 - 09/2014
3	Anovulation 06/2021 - 05/2012
3	Wounds and Injuries (Trauma) 01/2021 - 10/2010
3	Liver Diseases (Liver Disease) 01/2019 - 02/2006
3	Cicatrix (Scar) 01/2016 - 10/2009
3	Hyperplasia 07/2014 - 11/2005
3	Osteoporotic Fractures 01/2008 - 06/2005
2	Stroke (Strokes) 02/2022 - 12/2014
2	Anemia 01/2022 - 07/2015
2	Glucose Intolerance 01/2021 - 01/2019
2	Diabetes Mellitus 01/2021 - 03/2014
2	Fibrosis (Cirrhosis) 01/2019 - 11/2016
2	Lower Urinary Tract Symptoms 01/2019 - 02/2010
2	Lung Neoplasms (Lung Cancer) 12/2018 - 01/2017
2	Skin Neoplasms (Skin Cancer) 12/2018 - 02/2015

Drug/Important Bio-Agent (IBA)

70	AndrogensIBA 11/2022 - 07/2002
53	Testosterone (Sustanon)FDA Link 10/2022 - 01/2003
19	Dihydrotestosterone (Androstanolone)IBA 01/2022 - 10/2003
17	Hormones (Hormone)IBA 01/2022 - 01/2003
17	Estradiol (Delestrogen)FDA LinkGeneric 12/2021 - 06/2004
16	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 06/2003
11	Estrogens (Estrogen)FDA Link 09/2020 - 07/2002
10	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2003
9	Gonadal Steroid Hormones (Sex Hormones)IBA 02/2022 - 07/2002
8	Pharmaceutical PreparationsIBA 01/2022 - 07/2009
7	Proteins (Proteins, Gene)FDA Link 10/2022 - 09/2008
6	omega-Chloroacetophenone (Mace)IBA 02/2022 - 01/2020
6	SteroidsIBA 01/2022 - 06/2007
6	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2019
5	Sex Hormone-Binding GlobulinIBA 10/2022 - 06/2007
5	CholesterolIBA 01/2020 - 10/2003
5	Vitamin D FDA LinkGeneric 12/2017 - 10/2010
4	Dehydroepiandrosterone (DHEA)IBA 01/2022 - 01/2017
4	Insulin (Novolin)FDA Link 01/2021 - 05/2012
4	25-hydroxyvitamin DIBA 12/2017 - 09/2013
4	Biological ProductsIBA 03/2015 - 11/2008
3	Hemoglobins (Hemoglobin)IBA 01/2022 - 07/2015
3	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2022 - 11/2021
3	GonadotropinsIBA 12/2021 - 11/2005
3	AntralIBA 06/2021 - 06/2012
3	Testosterone CongenersIBA 01/2021 - 08/2014
3	Estrone FDA Link 09/2020 - 08/2011
3	1,25-dihydroxyvitamin DIBA 12/2017 - 09/2013
3	AlbuminsIBA 07/2017 - 07/2010
3	Diphosphonates (Bisphosphonates)IBA 01/2015 - 02/2006
3	Prostate-Specific Antigen (Semenogelase)IBA 04/2012 - 10/2006
2	CytokinesIBA 01/2022 - 01/2019
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2022 - 12/2021
2	Follicle Stimulating Hormone (Follitropin)FDA Link 12/2021 - 08/2015
2	baysilon (polydimethylsiloxane)IBA 11/2021 - 01/2019
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2019
2	testosterone undecanoateIBA 01/2021 - 03/2010
2	AntioxidantsIBA 01/2021 - 01/2020
2	Therapeutic UsesIBA 01/2021 - 01/2017
2	Triglycerides (Triacylglycerol)IBA 01/2021 - 01/2020
2	CollagenIBA 08/2020 - 06/2004
2	HDL CholesterolIBA 01/2020 - 07/2017
2	Androgen Antagonists (Antiandrogens)IBA 01/2018 - 10/2015
2	Sirtuin 1IBA 07/2017 - 01/2011

Therapy/Procedure

19	Therapeutics 11/2022 - 01/2003
9	Activities of Daily Living (ADL) 10/2021 - 01/2012
3	Transplantation 01/2022 - 12/2016
3	Polypharmacy 01/2022 - 09/2012
3	Castration 01/2018 - 01/2005
2	Injections 07/2021 - 03/2010
2	Intramuscular Injections 01/2021 - 03/2010